In this study, the antiulcerogenic aftereffect of a baptize abstract acquired from the lichen breed Usnea longissimus extract was advised application indomethacin-induced abscess models in rats. Experimental groups consisted of six rats. Antiulcerogenic activities of 50, 100 and 200mg/kg physique wt. doses of the baptize abstract were bent by comparing the abrogating (treated alone with indomethacin) and absolute (ranitidine) ascendancy groups. Although all doses of the baptize abstract of U. longissima showed cogent antiulcerogenic action as compared to abrogating ascendancy groups, the accomplished action was empiric with 100 mg/kg physique wt. doses (79.8%). The baptize abstract of U. longissima showed abstinent antioxidant action if compared with trolox and ascorbic acids acclimated as absolute antioxidants. In addition, the activities of antioxidant enzymes [superoxide dismutase (SOD), catalase (CAT) and glutathione S-transferase (GST)] were bent in the abdomen tissues of rats and compared with those of the abrogating and absolute ascendancy groups to betrayal the furnishings of antioxidant enzymes on antiulcerogenic activity. SOD and GST enzymes activities in indomethacin-administrated tissues were bargain decidedly by indomethacin in allegory to ascendancy groups. These enzymes were activated, however, by the baptize extracts of U. longissima. In adverse to SOD and GST activities, CAT action was added by indomethacin and bargain by all doses of U. longissima and ranitidine. The present after-effects announce that the baptize abstract of U. longissima has a careful aftereffect in indomethacin-induced ulcers, which can be attributed to its antioxidant potential.
