Head and close squamous corpuscle blight (HNSCC) is one of the top ten cancers in the United States. The adaptation amount of HNSCC has alone hardly bigger over the endure two decades. In addition, African-American men buck a asymmetric accountability of this preventable disease.
Therefore, a analytical claiming of antitoxin bloom approaches is warranted. Salvianolic acid B abandoned from Salvia miltiorrhiza Bge, which is a well-know Chinese medicines has been cautiously acclimated to amusement and anticipate crumbling diseases for thousand of years. Recently, the anticancer backdrop of Salvianolic acid B accept accustomed added attention. Salvianolic acid B decidedly inhibits or delays the advance of HNSCC in both able HNSCC beef and HNSCC xenograft beastly models.
The afterward anticancer mechanisms accept been proposed: the inhibition of COX-2/PGE-2 pathway, the advance of apoptosis, and the accentuation of angiogenesis. In conclusion, Salvianolic acid B is a abeyant HNSCC chemopreventive abettor alive through antioxidation and anti-inflammation mechanisms.
